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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
UBE4A
All Species:
30.91
Human Site:
S105
Identified Species:
48.57
UniProt:
Q14139
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14139
NP_004779.2
1066
122561
S105
N
S
D
P
S
L
K
S
G
N
G
I
P
S
R
Chimpanzee
Pan troglodytes
XP_001161169
1066
122495
S105
N
S
D
P
S
L
K
S
G
N
G
I
P
S
R
Rhesus Macaque
Macaca mulatta
XP_001097812
1067
122494
S105
N
S
D
P
S
L
K
S
G
N
G
I
P
S
R
Dog
Lupus familis
XP_850081
1066
122542
S105
N
S
D
P
S
L
K
S
G
N
G
I
P
S
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9ES00
1173
133285
F179
D
R
D
R
D
V
I
F
L
S
S
L
S
A
Q
Rat
Rattus norvegicus
Q6P7A2
1066
122361
S105
N
S
D
P
N
L
K
S
G
N
G
I
P
S
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026081
1074
123247
S106
N
S
D
P
S
M
K
S
G
N
G
I
P
A
R
Frog
Xenopus laevis
NP_001084506
1072
122544
S104
N
S
D
P
S
L
K
S
G
S
G
I
P
L
L
Zebra Danio
Brachydanio rerio
XP_001922961
1078
122949
S108
N
S
D
P
S
L
R
S
G
N
G
I
P
P
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609060
993
113046
I118
R
K
I
D
C
S
K
I
L
A
L
I
L
N
N
Honey Bee
Apis mellifera
XP_393070
965
109934
F96
H
Q
K
R
R
L
I
F
V
N
V
D
S
I
E
Nematode Worm
Caenorhab. elegans
Q09349
980
113212
A100
F
I
D
P
D
I
I
A
G
C
R
E
E
D
A
Sea Urchin
Strong. purpuratus
XP_786748
942
107668
E108
N
I
D
M
A
L
F
E
R
L
L
L
P
D
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LF41
1038
117510
I125
L
A
V
S
Y
C
R
I
H
L
G
N
P
D
M
Baker's Yeast
Sacchar. cerevisiae
P54860
961
109887
I95
Q
E
I
D
R
L
V
I
G
Y
G
V
V
A
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
98.1
98.6
N.A.
24.6
97
N.A.
N.A.
87.7
79.7
76.7
N.A.
33.1
36.5
22.9
32.7
Protein Similarity:
100
100
98.5
99.4
N.A.
45.2
99
N.A.
N.A.
94.3
90.8
87.4
N.A.
51.3
54.5
42.5
52.2
P-Site Identity:
100
100
100
100
N.A.
6.6
93.3
N.A.
N.A.
86.6
80
86.6
N.A.
13.3
13.3
20
26.6
P-Site Similarity:
100
100
100
100
N.A.
46.6
100
N.A.
N.A.
100
86.6
93.3
N.A.
20
20
33.3
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
25.3
22.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
43.9
41.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
0
7
0
0
7
0
7
0
0
0
20
7
% A
% Cys:
0
0
0
0
7
7
0
0
0
7
0
0
0
0
0
% C
% Asp:
7
0
74
14
14
0
0
0
0
0
0
7
0
20
0
% D
% Glu:
0
7
0
0
0
0
0
7
0
0
0
7
7
0
7
% E
% Phe:
7
0
0
0
0
0
7
14
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
67
0
67
0
0
0
0
% G
% His:
7
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% H
% Ile:
0
14
14
0
0
7
20
20
0
0
0
60
0
7
0
% I
% Lys:
0
7
7
0
0
0
54
0
0
0
0
0
0
0
0
% K
% Leu:
7
0
0
0
0
67
0
0
14
14
14
14
7
7
7
% L
% Met:
0
0
0
7
0
7
0
0
0
0
0
0
0
0
7
% M
% Asn:
60
0
0
0
7
0
0
0
0
54
0
7
0
7
7
% N
% Pro:
0
0
0
60
0
0
0
0
0
0
0
0
67
7
7
% P
% Gln:
7
7
0
0
0
0
0
0
0
0
0
0
0
0
7
% Q
% Arg:
7
7
0
14
14
0
14
0
7
0
7
0
0
0
47
% R
% Ser:
0
54
0
7
47
7
0
54
0
14
7
0
14
34
7
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
7
0
0
7
7
0
7
0
7
7
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
7
0
0
0
0
7
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _